Plasdone® S-630 Copovidone
 
 
 
 
 

Plasdone® S-630 Copovidone

Plasdone S-630 copovidone is a synthetic, 60:40, linear, random copolymer of N-vinyl-2-pyrrolidone and vinyl acetate. The addition of vinyl acetate to the vinylpyrrolidone polymer chain reduces hydrophilicity and glass transition temperature (Tg) of the polymer relative to polyvinyl pyrrolidone (PVP) homopolymers. As a result, Plasdone S-630 copolymer is an excellent adhesive material and a tougher, more flexible film former than PVP homopolymer.

Product Name

K-Value

Typical Weight Average Molecular Weight (Mw)

Pharmacopeial Name

Monograph Compliance

USP/NF

Ph. Eur.

JPE

Plasdone
S-630

25-32

40,000

Copovidone

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*Plasdone S-630 copolymer conforms to the JPE monograph specifications for Copolyvidone

Download Plasdone S-630 Product Overview.

Benefits and applications

  • Serves as a tablet binder in dry granulations and direct compression tablet processes

  • Improves compactability of other binders and fillers in direct compressison tablet process

  • Improves solubility and enhances bioavailability of drug actives

  • Gives excellent performance as a binder in moisture sensitive formulations

  • Possesses excellent film forming properties and high substantivity to skin

  • USP verified